Types of Blood Disorders

Many blood disorders take their name from the element of the blood they impact.
The following types are blood disorders that affect a decrease in blood components or affect their function:

  • Leukemia: A group of cancers that affect the blood and bone marrow, leading to abnormal white blood cell production. Research in leukemia encompasses various aspects such as understanding the genetic mutations driving the disease, developing targeted therapies, and improving treatment outcomes.
  • Sickle Cell Disease (SCD): Sickle cell disease is a genetic disorder affecting hemoglobin production, leading to abnormal red blood cells. Research in sickle cell disease focuses on finding new treatments to alleviate symptoms, prevent complications, and ultimately cure the disease through approaches like gene therapy and stem cell transplantation.
  • Hemophilia: Hemophilia is a genetic bleeding disorder characterized by a deficiency in clotting factors. Research in hemophilia aims to improve clotting factor replacement therapies, develop gene therapies to correct the underlying genetic defects, and explore novel treatment modalities like gene editing.
  • Thalassemia: Thalassemia is a group of inherited blood disorders involving abnormal hemoglobin production. Research in thalassemia focuses on developing better supportive care strategies, such as blood transfusions and iron chelation therapy, as well as exploring curative approaches like gene therapy and bone marrow transplantation.
  • Myelodysplastic syndromes (MDS): Myelodysplastic syndromes are a group of disorders characterized by dysfunctional blood cell production in the bone marrow. Research in MDS involves understanding the underlying biology of the disease, identifying prognostic markers, and developing targeted therapies to improve patient outcomes.
  • Immune thrombocytopenic purpura (ITP): ITP is an autoimmune disorder characterized by low platelet counts due to immune-mediated destruction of platelets. Research in ITP focuses on elucidating the mechanisms of autoimmune dysregulation, developing novel immunomodulatory therapies, and optimizing treatment strategies to achieve durable remission.
  • Leukopenia: Leukopenia is a decrease in the number of white blood cells, impairing the body's ability to fight infections and increasing susceptibility to illness.
  • Thrombocytopenia: Thrombocytopenia is a condition characterized by a low platelet count in the blood, leading to an increased risk of bleeding and bruising.

Types of blood disorders that increase blood components are:

  • Erythrocytosis – if the disorder includes red blood cells
  • Leukocytosis – if the disorder causes white blood cells
  • Thrombocythemia or thrombocytosis – if the disorder distresses platelets

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Related Associations: Societatii Române de Hematologie | The Hematological Section of the Serbian Health Association | Slovenská Hematologická a Transfuziologická Spolocnost | Zdruzenja Hematologov Slovenije  | Sociedad Española de Hematología y Hemoterapia | Swedish Society of Hematology | Schweizerische Gesellschaft für Hämatologie  | Nederlandse Vereniging voor Hematologie

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